When mathematicians see someone write "e = 8" on an MIT entrance exam from 1869, they collectively lose their minds! The meme shows historical figures (including what appears to be Euler himself) trying to restrain someone who's witnessing this mathematical blasphemy. It's like catching someone claiming the Earth is flat at a NASA conference!
The joke references how mathematicians get irrationally upset (pun intended) about approximations. While engineers might round π to 3 for practical calculations, seeing the mathematical constant e (approximately 2.71828) defined as 8 would make any mathematician need therapy. The title "π=3 Is So 21st Century" suggests we've moved beyond that old mathematical sin to commit even more outrageous ones!