Cosmic explorers wondering if they can sail to the edge of the universe is peak cosmology humor! The CMB (Cosmic Microwave Background) is literally the oldest light in the universe - a remnant radiation from about 380,000 years after the Big Bang. It's basically the universe's baby photo!
The joke plays on the old "flat Earth" idea where sailors feared falling off the edge of the world. But with the CMB, there's no "edge" to fall off - it's the furthest we can see in all directions! It's like asking what's north of the North Pole or what's before time began.
Trying to sail beyond the CMB would be like trying to look behind a cosmic wall paper that surrounds our entire observable universe. Sorry explorers, this is one voyage that would require breaking the laws of physics!