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The universal experience of being a chemist summed up in four panels! Proudly declaring your profession only to be immediately cut off with "Can you make meth?" or "Can you make bombs?" before you can even explain how you're actually developing sustainable catalysts or studying protein folding. The immediate "NO" with that dead-inside expression is the scientific equivalent of retail workers hearing "it must be free then" when an item doesn't scan. Chemistry: where everyone assumes you're either Walter White or about to blow something up, and never the person who just wants to talk about hydrogen bonding.

For the chemistry nerds who understand electron configurations! The guy labeled "3d10" (completely filled d-orbital) keeps getting rejected by people with different electron configurations. In the top panel, the woman with "1s2, 2s2, 2p6, 3s2, 3p6" (the configuration of argon) walks away because noble gases don't want to bond—they're already stable! In the bottom panel, "4s2" (an alkali earth metal electron structure) is pushing "3d10" away. It's basically electron dating drama—transition metals getting friendzoned because they're too energetically stable. The periodic table's version of "it's not you, it's me."

Fluorine isn't just chasing Sully through the hallways of Monsters University - it's chasing electrons from literally anything on the periodic table! With its 7 valence electrons, fluorine is just one shy of a full octet, making it the most electronegative element in existence. It will straight-up mug other elements for that sweet, sweet electron to achieve noble gas configuration. Even noble gases aren't safe from this electron-hungry monster. Chemistry professors weren't kidding when they said fluorine doesn't ask for electrons - it takes them.

Chemical engineers have mastered the dark arts of dimensional analysis, where they routinely juggle dimensionless quantities like Reynolds numbers and Prandtl numbers. But inventing a 23rd one? Pure madness! In dimensional analysis, we combine physical variables to create ratios that have no units, making equations more elegant. The frantic chalkboard scribbling perfectly captures that moment when you're frantically trying to force-fit variables into some coherent dimensionless group while your professor watches in horror. The real magic trick isn't just solving the equation—it's convincing yourself it actually means something!

Chemistry puns that physically hurt! This diagram shows the conversion of Dewar benzene to either regular benzene or "argh" through disrotatory or conrotatory ring opening. The joke is that "argh" isn't a real molecule—it's just the sound you make when organic chemistry causes you pain. The title's "pericycle" reference is a clever nod to pericyclic reactions, which is exactly what's happening in these transformations. It's like the molecule itself is screaming in agony during its structural rearrangement. Only chemists would turn molecular suffering into humor.

The perfect encapsulation of organic chemistry lab trauma! While geometry gives us nice predictable shapes with fancy Greek names, recrystallization gives us... absolutely nothing. That beautiful theoretical 98% yield your professor promised? More like "Your%yieldisGON" because those precious crystals decided to take a permanent vacation. The meme brilliantly captures that soul-crushing moment when you realize your painstaking 6-hour synthesis produced approximately three sad crystals, and your lab report is due tomorrow. Chemistry doesn't care about your GPA or your sleep schedule!