The chemistry literature: "Just follow our simple procedure for a 98% yield!" Reality: You're stepping on rakes like you're auditioning for a slapstick comedy. The published methods are basically fairy tales where everything works perfectly, while you're in the lab triple-checking compounds, drying solvents until they're practically mummified, using Schlenk techniques that would impress NASA, and still getting yields that would make your PI weep. Chemistry papers should come with a disclaimer: "Results obtained by a wizard who performed this reaction exactly once under perfect planetary alignment. Your mileage may drastically vary."