The evolution of lab safety is hilariously captured here! The 1925 chemist (portrayed by buff Doge) casually announces mouth-pipetting concentrated sulfuric acid (H₂SO₄) - an incredibly dangerous practice that would literally dissolve your insides. Meanwhile, modern chemists (represented by wimpy Doge) panic over a microscopic drop of dilute acetic acid (basically fancy vinegar) on their protective glove.
What makes this extra spicy is that the concentration difference is astronomical - we're talking about comparing battery acid to something you put on your salad. The 0.00001M acetic acid is roughly 500,000 times more dilute than household vinegar. Chemistry veterans know this struggle - we've gone from recklessly tasting unknown compounds to filling out three safety forms before opening a bottle of water.