Hydrogen Compounds: From Harmless To... Helium?

The chemical progression from harmless to horrifying is perfect! Starting with water (H₂O) where SpongeBob is happily floating, then sulfuric acid (H₂SO₄) where he's still okay but slightly concerned. Then we hit mustard gas (S(CH₄Cl)₂) and SpongeBob is rightfully worried. The fourth panel shows sarin nerve agent (C₁₁H₂₆NO₂PS) with buff SpongeBob looking distressed. Finally, the punchline - helium (He) with the skull and crossbones, where SpongeBob is completely deformed! The irony is magnificent - helium is an inert noble gas that's harmless to humans (besides the squeaky voice effect), while the previous compounds are increasingly dangerous. It's the perfect chemistry nerd joke that flips expectations - the supposedly deadliest substance is actually the safest! Chemistry students everywhere are snorting into their Erlenmeyer flasks.