Tumor suppressors Memes

The cellular Gandalf has spoken! When a cell tries to sneak from G1 to S-phase with damaged DNA, tumor suppressor proteins pRb and p53 transform into molecular bouncers at the cell cycle checkpoint. These guardians of genetic integrity basically slam their staffs down and yell "YOUR MUTATION SHALL NOT PASS!" Seriously though, without these proteins playing defense, we'd all be walking tumor factories. Next time you're cancer-free, thank your p53 - the unsung wizard of your cellular Middle Earth.