Evolution's twisted sense of humor in action! Sickle cell trait? *Panic* But wait—it makes you malaria-resistant? *Kalm* Oh no, you got TWO copies of the gene?! *MAXIMUM PANIC* This is natural selection's version of "good news, bad news, TERRIBLE news." Mother Nature basically saying "I'll protect you from mosquitoes, but at what cost?!" The ultimate genetic trade-off that proves biology has a dark sense of humor. Like getting superpowers but with the WORST side effects package!