Primary school: "The mitochondria is the powerhouse of the cell!" *happy innocent face* College: *sobbing face* "Here's the actual cellular respiration process involving glycolysis, pyruvate oxidation, Krebs cycle, and electron transport chain with 30+ enzymes, cofactors, and intermediates that will be on your exam Monday." That simplified mitochondria line is like being told babies come from storks, then suddenly having to perform a C-section. The biochemical betrayal is real!