Rough er Memes

The endoplasmic reticulum (ER) is truly the cellular Jekyll and Hyde! This organelle exists in two forms: smooth ER (no ribosomes, sleek like a freshly waxed sports car) and rough ER (covered in ribosomes, bumpy like a teenage face before prom). It's literally the only correct answer to "what can be smooth but also rough" - unless you're talking about my lab notes after 48 hours without sleep! The ER is basically that friend who's both organized AND chaotic depending on which side of their personality you're dealing with. Biology's ultimate dual-personality organelle!