Polyadenylation Memes

When your mRNA gets polyadenylated, it's literally just adding a bunch of A's to the 3' end! That's why SpongeBob is screaming "AAAAAAAA" – he is the poly-A tail! It's like your genetic material putting on its fancy stability coat before heading out into the cytoplasm. Without this A-mazing tail, your mRNA would be destroyed faster than my lab notes in a coffee spill catastrophe! The longer the AAAAA scream, the longer your mRNA survives the cellular hunger games!