Esterification Memes

Just like 6-hydroxyhexanoic acid forms a ring by attacking itself, we all curl up and crash after a long day in the lab. The molecule's OH group is practically begging to react with that carboxylic acid end—it's basically chemistry's version of fetal position. Nature's way of saying "I'm done with today's nonsense." Next time your professor asks why you understand cyclization so well, just tell them it's because you practice it nightly after their impossible exams.