Binding Memes

Posts tagged with Binding

Molecular Third-Wheeling

Molecular Third-Wheeling
Poor little substrate just sitting there watching the enzyme hook up with the inhibitor instead! In biochemistry, competitive inhibition is basically molecular third-wheeling - the inhibitor has a similar structure to the substrate and steals its spot in the enzyme's active site. The yellow figurine's dejected posture perfectly captures that "I came all this way for nothing" feeling when you're blocked from your binding site. Just like showing up to a party only to find your crush already dancing with someone else!

The Competition Is Strong Here, But We Clearly Know Who's Getting To See That Active Site Tonight

The Competition Is Strong Here, But We Clearly Know Who's Getting To See That Active Site Tonight
Biochemistry dating drama at its finest! The enzyme is clearly eyeing that substrate while the competitive inhibitor sits there helplessly. In enzymatic reactions, competitive inhibitors and enzymes both fight for the substrate's active site—but the enzyme usually wins due to its perfect molecular fit. That substrate is about to experience some serious conformational change tonight while the inhibitor is left wondering why it spent all that energy on binding affinity just to get ghosted. Molecular third-wheeling has never been so awkwardly relatable!

Active Site-Blocked

Active Site-Blocked
Classic competitive inhibition in action. The enzyme's trying to bind with its substrate, but the inhibitor molecule swoops in and blocks the reaction. Just like that awkward moment when you're about to talk to someone at a conference and a more charismatic researcher interrupts. The substrate's facial expression says it all - "I was literally just about to catalyze that reaction." Meanwhile, the enzyme is left with nothing but unfulfilled active sites and regret.